Receptor Endocytosis and Signalling in Health and Disease, Part B, Volume 196: Unlocking the Secrets of Cellular Communication

This comprehensive volume, edited by Indra Mani, delves into the intricacies of receptor endocytosis and signalling, covering a wide range of receptors associated with various organs and their crucial roles in maintaining normal bodily functions.

Navigating the Complexities of Receptor Endocytosis and Signalling

The book explores in-depth the internalization and signalling pathways of numerous receptors, including:

• Somatostatin receptors: Uncovering their role in brain and peripheral function
• Mas receptor: Elucidating its signalling and trafficking mechanisms in health and disease
• AMPA receptors: Examining their endocytosis and implications in neurological conditions
• Dopamine receptors: Deciphering their endocytosis and signalling mechanisms in the brain
• 5-HT1-2 and GABA receptors: Delving into their roles in neurotransmission and synaptic plasticity
• GPCR, nuclear receptor, and integrin receptors: Investigating their structures, functions, and cellular processes
• BCR and CRHR1 receptors: Unraveling their endocytosis and spatiotemporal regulation of receptor signalling

Advances in Receptor Signalling and Trafficking

This volume also provides cutting-edge insights into the molecular level understanding of G-protein-coupled receptor signalling, nuclear receptor structure and function, and integrin receptor trafficking in health and disease.

Furthermore, the book sheds light on the importance of receptor endocytosis in various physiological and pathological contexts, including:

• Liver function and LXRs signalling
• Cardiovascular diseases and LDL receptor internalization

By exploring the complexities of receptor endocytosis and signalling, this volume offers a comprehensive understanding of the intricate mechanisms underlying cellular communication in health and disease.

Book Details

Published by Elsevier Science, February 20, 2023

Language: English

ISBN: 9780323955591, 9780323955607