Epigenetic Cancer Therapy: A Comprehensive Guide to the Future of Cancer Management

By Steven Gray

Epigenetic Cancer Therapy, Second Edition offers a comprehensive discussion on healthy and aberrant epigenetic biology, along with new discoveries to improve our understanding of cancer epigenetics and therapeutics. The book encompasses large-scale intergovernmental initiatives, as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.

Since the publication of the first edition of this book, the field of epigenetics has undergone significant change. New epigenetic therapies have been designed and approved for clinical use. Our knowledge of the plasticity of the epigenome in cancer and disease has expanded dramatically, with increasing evidence linking pollution to epigenetic changes in cancer development.

This second edition has been fully updated to address these changes, along with promising therapeutic programs such as:

• CRISPR/Cas9 mediated approaches
• CAR-T based therapies
• Epigenetic priming
• Histone modifications
• Similar transformative advances across synthetic biology and cellular engineering

Product Details:

Language: English

Pages: 772

ISBN-10: 0323913679

ISBN-13: 978-0323913676

Publisher: Academic Press; 2nd edition (May 17, 2023)