Ion Channels in Cancer: Latest Advances and Therapeutic Targets

Edited by renowned expert Saverio Gentile, Ion Channels in Cancer, Volume 92 is a timely addition to the esteemed Current Topics in Membranes series. This authoritative volume presents cutting-edge research on the complex relationship between ion channels and cancer.

Exploring the Interplay of Calcium and Potassium Signals

In this comprehensive publication, leading international experts delve into the intricate interplay of calcium and potassium signals in cell cycle and cancer. Readers will gain insights into the non-conducting functions of ion channels in cancer and neurological disease, as well as the role of sodium channels in the progression of solid tumors.

Targeting Ion Channels for Cancer Therapy

The book highlights the potential of ion channels as therapeutic targets, including the mysterious Nav1.7 and its role in pain and cancer. Moreover, it explores the complexities of signaling pathways in cancer and the ion channels interactome as a novel therapeutic target.

Overcoming Cancer Drug Resistance with Ion Channels

Experts also discuss the crucial role of ion channels in cancer drug resistance and the potential of CLIC1 as a therapeutic target for malignant glioma. Additionally, the publication examines the surprising impact of amino acids on ion channels and transporters, going beyond their traditional role as building blocks.

Unveiling Tumor Vulnerability through Ion Channel Activation

Finally, the book reveals the exciting discovery of activating potassium channels to unveil tumor vulnerability, opening up new avenues for cancer research and treatment.

Published by Elsevier Science, this essential resource is a must-have for researchers, oncologists, and clinicians seeking to stay at the forefront of ion channel research and its applications in cancer therapy.

Key Features:

• Authored by leading international experts in the field
• Covers the latest advances in ion channel research and its implications for cancer treatment
• Provides insights into the complex interplay of ion channels and cancer
• Highlights the potential of ion channels as therapeutic targets
• Released November 2023, this is the latest update in the Current Topics in Membranes series