Medicinal Chemistry of Anticancer Drugs: A Comprehensive Guide

By Carmen Avendao, this third edition of Medicinal Chemistry of Anticancer Drugs offers an updated resource for students and researchers, focusing on the mechanism of action of antitumor drugs from a molecular perspective. It emphasizes the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents.

Antitumor chemotherapy is a rapidly evolving field of research, with a significant amount of new information generated annually. This new edition includes updated sections on the hot topics of:

• Cancer immunotherapy
• Cancer polypharmacology
• Multitargeted cancer therapy
• Medicinal chemistry of cancer diagnosis
• Theranostic anticancer agents
• Pre-mRNA processing in cancer

Although numerous books are available that deal with the clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the viewpoint of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy, and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references to reviews and the primary literature.

Key features of this book include:

• A resource organized consistently based on targets and mechanisms of action from a molecular point-of-view
• Focus on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents, providing a rationalization on the action of these types of drugs and the design of new active structures
• A large number of color figures that give information in a clear and concise way
• Extensive references to review articles and primary literature

This book is a valuable resource for anyone interested in the medicinal chemistry and drug design aspects of antitumor drugs. It provides a comprehensive overview of the field and serves as a starting point for further research.