Prostate cancer (PCa) is one of the most prevalent types of cancer in men worldwide, and despite advancements in treatment, it remains a leading cause of cancer-related deaths. The disease’s poor survival rates and resistance to cytotoxic and targeted therapies are significant challenges that need to be addressed.
A thorough understanding of the mechanisms responsible for therapy resistance in PCa is crucial for developing effective treatment strategies. Therapy Resistance in Prostate Cancer: Mechanisms and Insights provides researchers and clinicians with a comprehensive overview of current options and new therapies that can help overcome this resistance.
Delving deeper into the pathways behind chemotherapy resistance can lead to the discovery of new therapeutic targets for PCa. This knowledge can aid in the development of novel therapies that specifically target cancer stem cells (CSCs), eliminating the regenerating capacity of the tumor and overcoming therapy resistance.
This comprehensive guide tackles the topic of resistance from a broader perspective, exploring the role of the extracellular matrix and cancer stem cells in therapy resistance. By understanding the complex interactions between these factors, researchers can identify novel molecular biomarkers and potential therapeutic targets pertaining to the tumor microenvironment.
A key aspect of this book is its focus on the main pathways involved in PCa progression, providing a general view of the mechanisms responsible for chemotherapy resistance. This knowledge can aid in the development of more effective treatment strategies and improve patient outcomes.
Published by Academic Press, Therapy Resistance in Prostate Cancer: Mechanisms and Insights is set to release on October 24, 2023. This valuable resource is available in English and features sticky notes on Kindle Scribe. The ISBN number for this publication is 0443160325.
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