Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics: A Comprehensive Review

Authored by Sunny Ohia, this extensive handbook provides a detailed review of the fundamental aspects of ocular pharmacology and therapeutics, focusing on drug therapy, drug delivery, and the application of therapeutic medical miniature devices.

Understanding the Pharmacological Actions of Ocular Drugs

To comprehend the pharmacological actions of drugs acting on the eye, students and healthcare practitioners must grasp additional principles in basic and clinical sciences that are unique to this organ. As a sensory organ, the eye poses a unique challenge due to its inaccessibility to the systemic circulation, resulting from the blood-vitreous, blood-aqueous, and blood-retinal barriers.

Pharmacokinetic Principles and Ocular Drug Delivery

The administration of drugs for therapeutic effects in the eye necessitates an understanding of the physico-chemical properties of molecules and pharmacokinetic principles involved in accessing the site of action via topical, intracameral, and intravitreal administration. This handbook delves into the general principles of pharmacokinetics and pharmacodynamics of drugs as they pertain to the eye, and their role in combating ocular disorders and diseases.

Disease-Themed Approach to Ocular Pharmacology

Using a disease-themed approach, this comprehensive guide discusses the basic and clinical pharmacological principles involved in the therapy of various ocular diseases, including the ocular side effects of systemically-administered drugs, drugs used in ophthalmic surgery, and miscellaneous agents. The therapeutic utility of biologics, drug conjugates, combination products, gene, and cellular therapy are also covered in-depth.

A Valuable Resource for Healthcare Professionals and Students

This handbook serves as a primary and secondary source of reference, providing up-to-date information about the pharmacological mechanisms of action, pharmacokinetics, side effects, drug-drug interactions, and therapeutic indications of drugs for pharmacologists, pharmaceutical scientists, students in healthcare disciplines (nursing, pharmacy, optometry, medical), and practitioners in optometry and ophthalmology.

Key features of this handbook include:

• Explains the mechanisms of action, side-effects, and therapeutic uses of drugs, biologics, miniature devices, gene, and cellular therapies for the eye
• Provides a comprehensive review of the anatomy, physiology, biochemistry, pharmacology, microbiology, genetics, and pathology of parts of the eye involved in drug therapy to combat eye disorders and diseases
• Explores the pharmacological and clinical basis of drugs, drug conjugates, combination products used in the treatment of anterior and posterior segment diseases

Published by Elsevier Science, this invaluable resource is available in English and can be referenced by ISBN: 9780128192917 (Hardcover) and ISBN: 9780128192924 (E-book).