Current Topics in Nonclinical Drug Development: Volume 2

Edited by Philip Bentley, this comprehensive volume is the second installment in the CURRENT TOPICS IN NONCLINICAL DRUG DEVELOPMENT SERIES, providing an in-depth exploration of critical issues and current topics in nonclinical drug development.

This authoritative guide covers a wide range of individual topics and strategies in drug development, from compound characterization to drug registration. Featuring contributions from renowned experts in the field, the book discusses recent and rapid advances in technologies and associated changes in regulatory guidance.

Key Topics Covered:

• Evolution of Artificial Intelligence (AI) technologies and their impact on toxicologic pathology
• Current approaches to carcinogenicity testing and their implications
• Predicting drug-drug interactions: Strategies and best practices
• Understanding idiosyncratic drug reactions: Causes, mechanisms, and prevention
• Assessing cardiovascular risks beyond QT interval: A comprehensive approach
• The role of 3D cell cultures in toxicology and ADME: Advantages and applications
• Development of small molecule-antibody complexes: Opportunities and challenges
• Differentiating adverse from non-adverse findings in nonclinical studies: A guide

This invaluable resource is designed to aid toxicologists, toxicologic pathologists, consultants, regulators, study directors, and nonclinical scientists dealing with day-to-day issues encountered in drug development. It provides actionable insights and strategies for resolving these issues, making it an essential reference for academicians and graduate students pursuing research related to nonclinical drug development.

With its comprehensive coverage of current topics and expert contributions, Current Topics in Nonclinical Drug Development: Volume 2 is an indispensable tool for anyone involved in the drug development process.

Publisher: CRC Press
Publication Date: November 9, 2023
Language: English
ISBN: 9780367466688, 9781000961126