Unraveling the Complexity of Alzheimer’s Disease: Recent Advancements in Drug Design and Discovery

Edited by renowned experts in the field, Atta-ur-Rahman and Muhammad Iqbal Choudhary, this comprehensive compilation delves into the latest breakthroughs in Alzheimer’s disease (AD) research, providing invaluable insights for scientists, researchers, and healthcare professionals.

A Deeper Understanding of Alzheimer’s Pharmacotherapy

The book begins with an exhaustive overview of AD pharmacotherapy, highlighting the effectiveness of existing blockbuster drugs and the need for innovative approaches to tackle this complex neurodegenerative disorder.

Natural and Synthetic Small Molecules: Unlocking New Possibilities

The potential of both natural and synthetic small molecules is explored, shedding light on their role in AD treatment and prevention. The inhibition of cholinesterases, a crucial enzyme implicated in the onset and progression of AD, is also examined in depth.

BACE-1: A Promising Target for Alzheimer’s Drug Discovery

The role of beta-site APP clearing enzyme-1 (BACE-1) in the production of β-amyloid proteins, a hallmark of AD, is discussed at length. This section provides a thorough analysis of BACE-1 as a promising target for AD drug development, offering a glimmer of hope for the millions affected by this debilitating disease.

Featuring 16 comprehensive reviews written by leading global researchers, this compilation is an indispensable resource for anyone seeking to stay abreast of the latest developments in AD research and neurodegenerative disease drug development.

Key Highlights:

• Comprehensive overview of AD pharmacotherapy and existing drugs
• In-depth analysis of natural and synthetic small molecules
• Examination of BACE-1 and other promising targets for AD drug discovery
• Edited by renowned experts in the field of AD research and neurodegenerative disease drug development
• A valuable resource for scientists, researchers, and healthcare professionals

Product Details:

Pages: 784

Publisher: Elsevier

Publication Date: June 16, 2015

Language: English

ISBN-10: 0128039590

ISBN-13: 978-0128039595