Fighting Viral Diseases: Emerging Strategies in Antiviral Drug Development

Authored by renowned medicinal chemists Helga Rbsamen-Schaeff, Helmut Buschmann, Raimund Mannhold, and Jrg Holenz, this comprehensive book delves into the complexities of antiviral drug discovery and development, offering a roadmap for combatting Ebola, SARS Coronavirus, and other known and emerging human viruses.

Medicinal Chemistry Perspective on Antiviral Therapy

Building on the successes of the past decades, this book provides an in-depth exploration of the entire field of antiviral drug discovery and development from a medicinal chemistry perspective. The authors discuss antiviral drugs, targets, and viral disease mechanisms, shedding light on the most effective strategies for fighting viral diseases.

New Developments in Antiviral Drug Development

The book offers a timely outlook on emerging pathogens such as Ebola, Zika, West Nile, and Lassa, including a dedicated chapter on SARS Coronavirus-2, responsible for the ongoing pandemic. By examining the discovery and development process for antiviral agents for different classes of viruses and targets, the authors provide a comprehensive understanding of the field.

The book covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and explores novel antiviral strategies against emerging viruses. By summarizing the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, the authors provide valuable insights for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists.

Addressing the Challenges in Antiviral Drug Discovery

The book tackles practical and strategic challenges in the drug discovery and development process, including screening technologies, latency, and toxicity issues. By providing a comprehensive understanding of the complexities involved, the authors offer a valuable resource for those in the pharmaceutical industry and public health agencies.

With its focus on medicinal chemistry and pharmacological aspects, this book is an essential read for anyone involved in the fight against viral diseases. By exploring the latest developments in antiviral drug development, readers can gain a deeper understanding of the strategies and approaches necessary to combat the growing threat of viral diseases.

Book Details:

• Publisher: Wiley-VCH
• Edition: 1st edition
• Publication Date: January 31, 2022
• Language: English
• Pages: 528 pages
• ISBN-10: 3527343377
• ISBN-13: 978-3527343379