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Written by renowned medicinal chemists from academia and industry, this comprehensive book delves into the entire field of antiviral drug discovery and development from a medicinal chemistry perspective.
The book provides a thorough overview of antiviral drugs, targets, and viral disease mechanisms, with a special focus on emerging pathogens such as Ebola, Zika, West Nile, and Lassa. A dedicated chapter is also dedicated to SARS Coronavirus-2, the culprit behind the present pandemic.
By building on the successes of the past decades, New Drug Development for Known and Emerging Viruses describes the discovery and development process for antiviral agents for different classes of viruses and targets. This includes the experiences from the nine human viruses for which approved drugs are already on the market, such as HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV, and VZV.
The book covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and explores novel antiviral strategies against emerging viruses. Practical and strategic challenges in the drug discovery and development process are also addressed, including screening technologies, latency, and toxicity issues.
New Developments in Antiviral Drugs is an indispensable resource for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists. It will also be of great interest to those in the pharmaceutical industry and public health agencies.
Publisher: Wiley-VCH
Publication Date: January 31, 2022
Language: English
Format: Hardcover
Pages: 528
ISBN-10: 3527343377
ISBN-13: 978-3527343379
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