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Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations, 2nd Edition: Principles, Methods, and Applications in the Pharmaceutical Industry (EPUB)

Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations: A Comprehensive Guide

Authored by Sheila Annie Peters, this second edition book is a valuable resource for pharmaceutical professionals, bridging the gap between theory and practice in Physiologically Based Pharmacokinetic (PBPK) modeling.

Unlocking the Potential of PBPK Modeling in Drug Discovery and Development

Physiologically Based Pharmacokinetic (PBPK) modeling is a rapidly growing field that holds immense potential for improving drug discovery and development. This book provides a clear and concise understanding of PBPK principles, methods, and applications in the pharma industry. With a focus on practical applications, the author explores the vast possibilities of PBPK modeling in enhancing drug development processes.

New Features and Updates in the Second Edition

  • A brand-new section featuring case studies in different application areas, including drug-drug interaction, genetic polymorphism, renal impairment, and pediatric extrapolation.
  • Additional chapters covering model-informed drug development (MIDD) and current applications in the field.
  • Substantially revised chapters that simplify complex topics and offer a balanced view of both the opportunities and challenges of PBPK modeling.
  • Gain a deep understanding of the principles behind physiological modeling of pharmacokinetic processes, inter-individual variability, and drug interactions for small molecule drugs and biologics.
  • Explore the wealth of new figures and case studies showcasing the applications of PBPK modeling along the value chain in drug discovery and development.
  • Stay up-to-date with the latest regulatory guidelines on the reporting of PBPK modeling analysis.
  • Access a companion website containing code, datasets, explanations of case examples, and discussions of key developments in the field.

Benefits for Pharmaceutical Professionals

This book is an indispensable resource for beginning and intermediate practitioners across the pharmaceutical sciences in both industry and academia. With its comprehensive coverage of PBPK modeling, this book will help you:

  • Improve drug development processes through the application of PBPK modeling.
  • Enhance your understanding of PBPK principles and methods.
  • Stay current with the latest developments and regulatory guidelines in the field.

Get instant access to the companion website containing supplementary resources and stay ahead in the field of PBPK modeling.

Published by Wiley in September 2021, this book is a valuable addition to your pharmaceutical library. Order your copy today and unlock the full potential of PBPK modeling in drug discovery and development!

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