Drug Metabolism Handbook: Concepts and Applications in Cancer Research

Author: Ala F. Nassar

ISBN: 9781119851011, 9781119851028

Publication Date: November 11, 2022

Language: English

Publisher: Wiley

Book Description:

The newly revised second edition of Drug Metabolism Handbook: Concepts and Applications in Cancer Research offers a comprehensive explanation of drug metabolism concepts and their applications in drug development and cancer treatment. This book provides an incisive and robust exploration of the drug metabolism system, guiding readers through the latest tools and techniques used in research, pharmacology, and medicine. It discusses the creation of new molecular entities, drug development, troubleshooting, and other highly relevant concepts, guiding readers through new applications in pharmaceutical research, development, and assessment.

Key Features:

Metabolism Basics: The book offers an updated content on metabolism basics and the application of a variety of new techniques to cancer treatment, including mass spectrometry, imaging, metabolomics, and immunotherapy. It also offers in-depth case studies highlighting the role of metabolism in drug development.

Technologies for In Vitro and In Vivo Studies: Comprehensive discussions of technologies for in vitro and in vivo studies, including mass spectrometry and accelerating metabolite identification with mass spectrometry.

Drug Interactions: In-depth explorations of drug interactions, including discussions of enzyme inhibition and the characterization of cytochrome P450 mechanism-based inhibition.

Drug Toxicity: Fulsome treatments of drug toxicity, including the role of drug metabolism in toxicity, and allergic reactions to drugs.

Target Audience:

This book is perfect for medicinal chemists, pharmaceutical scientists, and toxicologists. It will also earn a place in the libraries of analytical chemists and drug discovery professionals.