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Neurons, the excitable cells of our nervous system, rely on ions and electrical signaling to communicate with each other. This intricate process enables them to control behavior, and at the heart of it lie ion channels. Ion channels are integral to neuronal excitability and synaptic transmission, and understanding their biology and function is crucial for neuroscientists, biophysicists, and neuropharmacologists.
The Oxford Handbook of Neuronal Ion Channels is an accessible and comprehensive reference that delves into the nature and properties of ion channels in neurons. This exhaustive guide explains how ion channels open and close, their selectivity for specific ions, and their role in generating action potentials. The handbook also explores in-depth specific classes of ion channels, including potassium channels, sodium channels, neurotransmitter-gated ion channels, and other specialized channels.
Furthermore, the handbook provides valuable insights into the contribution of ion channels to neuronal excitability and synaptic transmission. It also discusses channelopathies, a group of human diseases that can be caused by ion channel dysfunction, such as epilepsy, pain, and migraines.
This handbook is an indispensable resource for researchers and academics seeking to expand their knowledge of ion channel biology and function. With its in-depth explanations and expert contributions, it is an essential reference for anyone looking to gain a deeper understanding of the complex world of neuronal ion channels.
Published by Oxford University Press on February 10, 2023, this handbook is a testament to the importance of ion channels in understanding the intricacies of the nervous system.
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