Comprehensive Guide to Anesthesia and Analgesia in Laboratory Animals

By Melissa Dyson, Paulin Jirkof, Jennie Lofgren, Elizabeth Nunamaker, Daniel Pang

Focus: Anesthesia and Analgesia in Laboratory Animals is a comprehensive guide that focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental interventions in laboratory animals. This fully revised and updated edition provides the reader with the latest agents, methods, and techniques for anesthesia and analgesia, ensuring humane, reproducible, and successful procedural outcomes.

Ethical, Regulatory, and Scientific Considerations

This section covers the essential ethical, regulatory, and scientific considerations that researchers and veterinarians must be aware of when conducting experiments involving animals. It emphasizes the importance of animal welfare and the need for rigorous protocols to ensure the highest standards of research.

Principles of Anesthesia and Analgesia

This section delves into the fundamental principles of anesthesia and analgesia, providing an in-depth understanding of the different types of anesthesia, their mechanisms of action, and their applications in various laboratory animal species. It also discusses the importance of pain management and the various methods available for assessing and managing pain in laboratory animals.

Anesthetic Equipment and Monitoring

This section is dedicated to the anesthetic equipment and monitoring techniques used in laboratory animal research. It covers the different types of anesthetic machines, monitoring devices, and safety protocols that are essential for ensuring the well-being of the animals during and after anesthesia.

Periprocedural Care

This section focuses on the critical aspects of periprocedural care, including pre-anesthetic preparation, intraoperative management, and post-anesthetic recovery. It provides practical advice on how to optimize animal care and minimize potential complications during these critical phases.

Species-Specific Considerations

This section offers dedicated chapters on the specific anesthetic and analgesic requirements of various laboratory animal species, including rodents, rabbits, dogs, cats, and non-human primates. Each chapter covers relevant anatomy, physiology, and behavior, providing researchers and veterinarians with the knowledge they need to tailor their anesthetic and analgesic protocols to the specific needs of each species.

Practical Applications and Case Studies

This final section presents practical applications and case studies that illustrate the successful implementation of the principles and techniques described in the book. It includes real-world examples of anesthetic and analgesic protocols used in various research settings, highlighting the challenges encountered and the solutions adopted.

Publication Details:

Publisher: Academic Press

Edition: 3rd edition

Publication Date: June 9, 2023

Language: English

Pages: 788

ISBN-10: 0128222158

ISBN-13: 978-0128222157