Optimizing Vaccine Testing: A Comprehensive Guide to the Guinea Pig Model

By Viviana Parreo, a renowned author in the field of veterinary medicine, this book provides an in-depth analysis of the development and statistical validation of a guinea pig model. This model serves as an alternative for potency testing of viral antigens found in combined vaccines used for cattle. These vaccines aim to control various syndromes such as respiratory, reproductive, and neonatal calf diarrhea.

The guinea pig model allows for the testing of vaccine quality for all viral antigens included in both aqueous and oil-adjuvanted formulations of bovine vaccines. This methodology has been recommended by CAMEVET as guidelines for 30 countries, including the United States.

Key Features of the Book

• A comprehensive review of combined vaccines used for cattle
• A detailed summary of animal models used for vaccine testing
• Focus on bovine herpesviruses, rotaviruses, parainfluenza, and bovine viral diarrhea virus
• Guidance on the effectiveness of the Guinea Pig model for testing vaccine immunogenicity

Product Details

Publisher: CRC Press

Publication Date: April 10, 2023

Language: English

ISBN: 9780367489861, 9781000850611